It is necessary to predict the influencing parameters on homogeneous watersheds for the future in order to make decision and correct management. In this research, 19 bioclimatic variables extracted from the ESM4-GFDL general circulation model based on ssp126 scenario and then were clustered in two statistical periods, including the years average of 1981-2010 and the average of 2041-2070, and also homogeneous watersheds were identified for two statistical periods. Also, the intensity of utility in homogeneous watersheds was investigated. The results showed that the homogeneous watersheds located in cluster 4, will be involved with the highest changes in increasing temperature and decreasing precipitation and it will cover about 16% of the area of Chaharmahal va Bakhtiari province. On the other hand, in all homogeneous watersheds, the seasonal changes in precipitation and average air temperatures of the wettest quarter have an increasing trend, which shows the disproportionate temporal distribution of precipitation will be occurred, then the problems lead to destructive floods, the reduction of plants and agricultural productions and destruction of native habitats of the regions. In this regard, Kohrang city has been studied as the most critical city and has the least desirable area, 23.38 and 22.35 in two periods, respectively.