Flood water spreading projections have been done with many objectives. One of these objectives is increasing vegetation cover. Flood spreading leads to increasing soil moisture and forage production. The purpose of this paper is to study the effect of flood spreading on quantitative changes in native vegetation cover in Sabzevar. At the first, canopy cover and vegetation density were measured by transect of 100m and plots of 225m2 (15×15), respectively. A region as a flood spreading area including three phases, two phases of Atriplex and one phase of Haloxylom was selected. Also, a region was considered as control area. Then, common species (endemic species) were compared in flood spreading region to control area. The results showed that water spreading has positive effects on endemic spices, especially in Haloxylon phase and these effects were significant at 1%. Flood spreading has no effect on canopy cover and vegetation density in Atriplex phase1 and the effects in Atriplex phase2 were negative. So, flood water has different effect on endemic species based on planted species in region.